Similac Advance vs. 360 vs. Sensitive vs. Total Comfort: Differences and Reviews 2024
About Similac
Similac is the #1 infant formula brand fed in hospitals
Similac formulas have no artificial growth hormones
Similac has no palm olein oil to support excellent calcium absorption
EBT eligible: Eligible to be purchased with supplemental nutrition assistance program (snap) benefits in select stores
For nearly a century, Similac has focused on innovations designed to meet the needs of babies and parents. Similac formulas are inspired by breast milk and designed to meet the nutrition needs of your baby while supporting their growth and development. Similac formulas can help give your little one a strong start and have important vitamins and minerals.
Most Similac formulas have their exclusive blend of DHA, lutein, and vitamin E to support baby's brain and eye development and are made with milk ingredients that do not have artificial growth hormones. Similac formulas have no palm olein oil. Similac oil blend allows for greater absorption of nutrients like calcium, compared to formulas made with palm olein oil.
History
Similac heritage—a spirit of innovation that began in 1925 and hasn’t stopped.
In 1903, the Wright brothers were inventing flight, the first World Series was played—and the Moores and Ross Milk Company was founded.
Two decades later, Moores and Ross developed their very first commercial, milk-based formula, Similac.
Moores and Ross continued to innovate its baby formula and bring new choices to parents. Today, that spirit lives on at Abbott as it continues to provide formula options like hypoallergenic, soy, organic, sensitive, and post-discharge preterm formulas.
Whether you choose to formula feed or supplement breastfeeding with formula, you can be confident in the nourishment of Similac. Similac strives to give babies a strong start by helping to keep them fed, happy, and healthy.
Similac Advance Infant Formula Reviews
Similac Advance is a nutritionally complete, milk-based, iron-fortified infant formula for baby’s first year. It has Similac exclusive blend of ingredients to support baby’s brain and eye development.
Features:
①Easy To Digest: Similac Advance is nutritionally complete and inspired by breast milk. |
| ②Supports Brain & Eyes: Has DHA and lutein, important ingredients found in breast milk. |
| ③Similac Advance is also kosher and halal. |
Similac 360 Total Care Infant Formula Reviews
Similac 360 Total Care infant formula has an exclusive blend of 5 HMO prebiotics structurally identical to those in breast milk. Their infant formula is designed to help support the immune system, brain development, and digestive health. Ingredients in Similac 360 Total Care are non-GMO.
Features:
①Has Their Closest Prebiotic Blend To That In Breast Milk: Similac 360 Total Care, their biggest formula breakthrough, has an exclusive blend of 5 HMO prebiotics structurally identical to those in breast milk. |
②Whole-Baby Support: Nutrition designed to help support the immune system, brain development, and digestive health. |
③Designed To Help Strengthen The Immune System: Similac 360 Total Care is designed to help strengthen baby’s immune system. |
Similac Sensitive Infant Formula Reviews
Similac Sensitiveis an easy-to-digest, milk-based infant formula designed for sensitive tummies. It’s complete nutrition for fussiness, gas, or mild spit-up. Their formula has their exclusive blend of nutrients to help support baby’s brain and eye development.
Features:
①Designed For Baby’S Fussiness & Gas: Their sensitive formula for babies is specially designed for fussiness and gas due to lactose sensitivity. |
| ②Supports Brain & Eyes: Has DHA and lutein, important ingredients found in breast milk. |
Similac Total Comfort Infant Formula Reviews
Similac Total Comfort formula is gentle on baby’s tummy; it has partially broken-down protein for easy digestion and prebiotics to support digestive health. It also contains their exclusive blend of ingredients to support baby’s brain and eye development. It’s a good choice for babies who have difficulty tolerating other milk-based formulas.
Features:
①Gentle Formula: Partially hydrolyzed whey protein allows for easy digestion. |
②Digestive Health: Prebiotics to stimulate the growth of good bacteria to support digestive health. |
| ③Supports Brain & Eyes: Has DHA and lutein, important ingredients found in breast milk. |
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Similac Advance vs. 360 Total Care vs. Sensitive vs. Total Comfort
Below, we will make a deep comparison between Similac Advance, 360 Total Care, Sensitive, and Total Comfort, so that you can purchase the one best for your baby.
1. At a Glance
| Advance | 360 Total Care | Sensitive | Total Comfort | |
| Price | $1.34 / oz | $1.62 / oz | $1.48 / oz | $1.42 / oz |
| Feeding needs | Everyday nutrition | Everyday nutrition | Fussiness & gas | Broken-down protein for easy digestion |
| Formula benefits | ①Milk-based; ②Iron-fortified. | ①Milk-based; ②Non-GMO; ③5 HMO Prebiotics. | ①Milk-based; ②Disgned for baby's fussiness, gas, or mild spit-up. | ①Broken-down protein for easy digestion; ②Prebiotics to support digestive health. |
DHA | ✔ | ✔ | ✔ | ✔ |
ARA | ✔ | ✔ | ✔ | ✔ |
Choline | ✔ | ✔ | ✔ | ✔ |
Inositol | ✔ | ✔ | ✔ | ✔ |
Iron | ✔ | ✔ | ✔ | ✔ |
Lactoferrin | × | × | × | × |
| MFGM | × | × | × | × |
Prebiotics | × | ✔ | × | ✔ |
| Vitamin D | ✔ | ✔ | ✔ | ✔ |
| Not for infants or children with galactosemia. | ||||
2. Nutrients [Serving Size: 100 Cal (5 fl oz, prepared as directed)]
Amount per serving | Advance | 360 Total Care | Sensitive | Total Comfort |
| Calories | 100 | 100 | 100 | 100 |
Volume | 148 mL | 148 mL | 148 mL | 148 mL |
Protein | 2.07 g | 2.07 g | 2.1 g | 2.32 g |
Fat | 5.6 g | 5.6 g | 5.4 g | 5.4 g |
Carbohydrate | 10.7 g | 10.5 g | 10.9 g | 10.7 g |
Water | 133 g | 134 g | 133 g | 133 g |
| Linoleic Acid | 1000 mg | 1000 mg | 1000 mg | 1000 mg |
Similac Total Comfort Infant Formula has the highest protein content.
3. Vitamins [Serving Size: 100 Cal (5 fl oz, prepared as directed)]
Amount per serving | Advance | 360 Total Care | Sensitive | Total Comfort |
Vitamin E | 1.5 IU | 1.5 IU | 1.5 IU | 1.5 IU |
Vitamin K | 8 mcg | 8 mcg | 8 mcg | 8 mcg |
Thiamin (Vitamin B1) | 100 mcg | 100 mcg | 100 mcg | 100 mcg |
Riboflavin (Vitamin B2) | 150 mcg | 150 mcg | 150 mcg | 150 mcg |
Vitamin B6 | 60 mcg | 60 mcg | 60 mcg | 60 mcg |
Vitamin B12 | 0.25 mcg | 0.25 mcg | 0.25 mcg | 0.25 mcg |
Niacin | 1050 mcg | 1050 mcg | 1050 mcg | 1050 mcg |
Folic Acid (Folacin) | 15 mcg | 15 mcg | 15 mcg | 15 mcg |
Pantothenic Acid | 450 mcg | 450 mcg | 450 mcg | 450 mcg |
| Biotin | 4.4 mcg | 4.4 mcg | 4.4 mcg | 4.4 mcg |
| Choline | 24 mg | 24 mg | 24 mg | 24 mg |
Inositol | 24 mg | 24 mg | 24 mg | 24 mg |
Vitamin C (Ascorbic Acid) | 9 mg | 9 mg | 24 mg | 24 mg |
Vitamin A | 300 IU | 300 IU | 300 IU | 300 IU |
Vitamin D | 60 IU | 60 IU | 60 IU | 60 IU |
The vitamin content of these four Similac Infant Formulas is exactly the same.
4. Minerals [Serving Size: 100 Cal (5 fl oz, prepared as directed)]
Amount per serving | Advance | 360 Total Care | Sensitive | Total Comfort |
Calcium | 78 mg | 78 mg | 84 mg | 105 mg |
Calcium | 3.9 mEq | 3.9 mEq | 4.2 mEq | 5.3 mEq |
Phosphorus | 42 mg | 42 mg | 56 mg | 75 mg |
Magnesium | 6 mg | 6 mg | 6 mg | 6 mg |
Iron | 1.8 mg | 1.8 mg | 1.8 mg | 1.8 mg |
Zinc | 0.75 mg | 0.75 mg | 0.75 mg | 0.75 mg |
Manganese | 5 mcg | 5 mcg | 5 mcg | 5 mcg |
Copper | 90 mcg | 90 mcg | 90 mcg | 90 mcg |
Iodine | 15 mcg | 15 mcg | 15 mcg | 15 mcg |
Selenium | 2 mcg | 2 mcg | 2 mcg | 2 mcg |
Sodium | 24 mg | 24 mg | 30 mg | 44 mg |
Sodium | 1 mEq | 1 mEq | 1.3 mEq | 1.9 mEq |
Potassium | 105 mg | 105 mg | 107 mg | 118 mg |
Potassium | 2.7 mEq | 2.7 mEq | 2.7 mEq | 3 mEq |
Chloride | 65 mg | 65 mg | 65 mg | 65 mg |
| Chloride | 1.8 mEq | 1.8 mEq | 1.8 mEq | 1.8 mEq |
The four Similac Infant Formulas differ only slightly in their mineral content.
5. Ingredients
①Similac Advance Infant Formula
Nonfat Milk, Lactose, High Oleic Safflower Oil, Whey Protein Concentrate, Soy Oil, Coconut Oil, Galactooligosaccharides*. Less than 2% of: Schizochytrium Sp. Oil†, M. Alpina Oil‡, Beta-Carotene, Lutein, Potassium Citrate, Calcium Carbonate, Ascorbic Acid, Soy Lecithin, Potassium Chloride, Magnesium Chloride, Ferrous Sulfate, Choline Bitartrate, Choline Chloride, Ascorbyl Palmitate, Salt, Taurine, Inositol, Zinc Sulfate, Mixed Tocopherols, d-Alpha-Tocopheryl Acetate, Niacinamide, Calcium Pantothenate, L-Carnitine, Vitamin A Palmitate, Copper Sulfate, Thiamine Hydrochloride, Riboflavin, Pyridoxine Hydrochloride, Folic Acid, Manganese Sulfate, Phylloquinone, Biotin, Sodium Selenate, Vitamin D3, Vitamin B12, Calcium Phosphate, Potassium Phosphate, Potassium Iodide, Potassium Hydroxide, and Nucleotides (Adenosine 5'-Monophosphate, Cytidine 5'-Monophosphate, Disodium Guanosine 5'-Monophosphate, Disodium Uridine 5'-Monophosphate).
* Prebiotic
† Source of DHA.
‡ Source of ARA.
Contains milk and soy ingredients.
②Similac 360 Total Care Infant Formula
Nonfat Milk, Lactose, High Oleic Safflower Oil, Whey Protein Concentrate, Soy Oil, Coconut Oil, Human Milk Oligosaccharides (2'-Fucosyllactose, Lacto-N-Tetraose, 3-Fucosyllactose, 6'-Sialyllactose, 3'-Sialyllactose)*. Less than 2% of: Schizochytrium Sp. Oil†, M. Alpina Oil‡, Beta-Carotene, Lutein, Potassium Citrate, Calcium Carbonate, Ascorbic Acid, Soy Lecithin, Potassium Chloride, Magnesium Chloride, Ferrous Sulfate, Choline Bitartrate, Choline Chloride, Ascorbyl Palmitate, Salt, Taurine, Inositol, Zinc Sulfate, Mixed Tocopherols, d-Alpha-Tocopheryl Acetate, Niacinamide, Calcium Pantothenate, L-Carnitine, Vitamin A Palmitate, Copper Sulfate, Thiamine Hydrochloride, Riboflavin, Pyridoxine Hydrochloride, Folic Acid, Manganese Sulfate, Phylloquinone, Biotin, Sodium Selenate, Vitamin D3, Vitamin B12, Calcium Phosphate, Potassium Phosphate, Potassium Iodide, Potassium Hydroxide, and Nucleotides (Adenosine 5'-Monophosphate, Cytidine 5'-Monophosphate, Disodium Guanosine 5'-Monophosphate, Disodium Uridine 5'-Monophosphate).
* HMO, not from human milk.
† Source of DHA.
‡ Source of ARA.
Contains milk and soy ingredients.
③Similac Sensitive Infant Formula
Corn Syrup, Milk Protein Isolate, High Oleic Safflower Oil, Sugar, Soy Oil, Coconut Oil. Less than 2% of: C. Cohnii Oil*, M. Alpina Oil†, Short-chain Fructooligosaccharides, Beta-Carotene, Lutein, Potassium Chloride, Sodium Citrate, Calcium Phosphate, Potassium Citrate, Soy Lecithin, Magnesium Phosphate, Choline Chloride, Ascorbic Acid, Inositol, Ascorbyl Palmitate, Ferrous Sulfate, Taurine, Calcium Carbonate, Choline Bitartrate, Zinc Sulfate, L-Carnitine, Mixed Tocopherols, Niacinamide, d-Alpha-Tocopheryl Acetate, Calcium Pantothenate, Magnesium Chloride, Vitamin A Palmitate, Copper Sulfate, Thiamine Hydrochloride, Riboflavin, Pyridoxine Hydrochloride, Folic Acid, Potassium Iodide, Manganese Sulfate, Phylloquinone, Biotin, Sodium Selenate, Vitamin D3, Vitamin B12, Potassium Hydroxide, and Nucleotides (Adenosine 5'-Monophosphate, Cytidine 5'-Monophosphate, Disodium Guanosine 5'-Monophosphate, Disodium Uridine 5'-Monophosphate).
* Source of DHA.
† Source of ARA.
Contains milk ingredients.
④Similac Total Comfort Infant Formula
Corn Maltodextrin, Whey Protein Hydrolysate, High Oleic Safflower Oil, Sugar, Soy Oil, Coconut Oil. Less than 2% of: Schizochytrium Sp. Oil*, M. Alpina Oil†, Short-chain Fructooligosaccharides, Beta-Carotene, Lutein, Calcium Citrate, Potassium Phosphate, Calcium Phosphate, Potassium Hydroxide, Salt, Magnesium Chloride, Ascorbic Acid, Choline Chloride, Inositol, Potassium Chloride, Sodium Citrate, Calcium Hydroxide, Potassium Citrate, Ferrous Sulfate, Taurine, Choline Bitartrate, Zinc Sulfate, Ascorbyl Palmitate, L-Carnitine, Niacinamide, Mixed Tocopherols, d-Alpha-Tocopheryl Acetate, Calcium Pantothenate, Copper Sulfate, Vitamin A Palmitate, Thiamine Hydrochloride, Riboflavin, Pyridoxine Hydrochloride, Folic Acid, Manganese Sulfate, Potassium Iodide, Phylloquinone, Biotin, Sodium Selenate, Vitamin D3, Vitamin B12, and Nucleotides (Adenosine 5'-Monophosphate, Cytidine 5'-Monophosphate, Disodium Guanosine 5'-Monophosphate, Disodium Uridine 5'-Monophosphate).
* Source of DHA.
† Source of ARA.
Contains milk ingredients.
6. Sizes
| Similac Advance | Similac 360 | Similac Sensitive | Similac Total Comfort |
|
|
|
|
7. Verdict
Which product to choose mainly depends on the baby's situation and actual needs. Here are some suggestions for you:
Similac Advance is a nutritionally complete, milk-based, iron-fortified infant formula for baby’s first year. It has their exclusive blend of ingredients to support baby’s brain and eye development.
Similac 360 Total Care infant formula has an exclusive blend of 5 HMO prebiotics structurally identical to those in breast milk. It’s also nutrition designed for immune support, brain development & digestive health.
Similac Sensitive is an easy-to-digest, milk-based infant formula designed for sensitive tummies. It’s complete nutrition for fussiness, gas, or mild spit-up. Similac formula has their exclusive blend of ingredients to help support baby’s brain and eye development.
Similac Total Comfort formula is gentle on baby’s tummy; it has partially brokendown protein for easy digestion and prebiotics to support digestive health. It also contains our exclusive blend of ingredients to support baby’s brain and eye development.
Price: 360 Total Care＞Sensitive＞Total Comfort＞Advance
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