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Similac Advance vs. 360 vs. Sensitive vs. Total Comfort: Differences and Reviews 2024

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Similac Advance vs. 360 vs. Sensitive vs. Total Comfort: Differences and Reviews 2024

For nearly a century, Similac has focused on innovations designed to meet the needs of babies and parents. Most Similac formulas have their exclusive blend of DHA, lutein, and vitamin E to support baby's brain and eye development and are made with milk ingredients that do not have artificial growth hormones. Similac formulas have no palm olein oil. Similac oil blend allows for greater absorption of nutrients like calcium, compared to formulas made with palm olein oil.

Similac offers a variety of infant formulas with different benefits, including: Similac Advance, 360, Sensitive, and Total ComfortInfant. But whcih one is best for you? What's the differences between them? Therefore in this Similac Advance vs. 360 vs. Sensitive vs. Total Comfort Infant Formulas comparison, we want to look at these four Infant Formula from top to bottom. This includes their product price, features, nutrients, ingredients, available formats and sizes! By the time you’re finished this guide, you will know all about Similac Advance, 360, Sensitive, and Total Comfort. That way, you’ll know which one is the best for your baby.

Cover Photo:similac.com

About Similac

Similac is the #1 infant formula brand fed in hospitals
Similac formulas have no artificial growth hormones
Similac has no palm olein oil to support excellent calcium absorption
EBT eligible: Eligible to be purchased with supplemental nutrition assistance program (snap) benefits in select stores

For nearly a century, Similac has focused on innovations designed to meet the needs of babies and parents. Similac formulas are inspired by breast milk and designed to meet the nutrition needs of your baby while supporting their growth and development. Similac formulas can help give your little one a strong start and have important vitamins and minerals.

Most Similac formulas have their exclusive blend of DHA, lutein, and vitamin E to support baby's brain and eye development and are made with milk ingredients that do not have artificial growth hormones. Similac formulas have no palm olein oil. Similac oil blend allows for greater absorption of nutrients like calcium, compared to formulas made with palm olein oil.

Source:similac.com

History

Similac heritage—a spirit of innovation that began in 1925 and hasn’t stopped.
In 1903, the Wright brothers were inventing flight, the first World Series was played—and the Moores and Ross Milk Company was founded.
Two decades later, Moores and Ross developed their very first commercial, milk-based formula, Similac.
Moores and Ross continued to innovate its baby formula and bring new choices to parents. Today, that spirit lives on at Abbott as it continues to provide formula options like hypoallergenic, soy, organic, sensitive, and post-discharge preterm formulas.

Whether you choose to formula feed or supplement breastfeeding with formula, you can be confident in the nourishment of Similac. Similac strives to give babies a strong start by helping to keep them fed, happy, and healthy.

Similac Advance Infant Formula Reviews

Similac Advance is a nutritionally complete, milk-based, iron-fortified infant formula for baby’s first year. It has Similac exclusive blend of ingredients to support baby’s brain and eye development.

Source:similac.com

Features:

①Easy To Digest: Similac Advance is nutritionally complete and inspired by breast milk.

②Supports Brain & Eyes: Has DHA and lutein, important ingredients found in breast milk.

③Similac Advance is also kosher and halal.

Similac 360 Total Care Infant Formula Reviews

Similac 360 Total Care infant formula has an exclusive blend of 5 HMO prebiotics structurally identical to those in breast milk. Their infant formula is designed to help support the immune system, brain development, and digestive health. Ingredients in Similac 360 Total Care are non-GMO.

Source:similac.com

Features:

①Has Their Closest Prebiotic Blend To That In Breast Milk: Similac 360 Total Care, their biggest

formula breakthrough, has an exclusive blend of 5 HMO prebiotics structurally identical to

those in breast milk.

②Whole-Baby Support: Nutrition designed to help support the immune system, brain

development, and digestive health.

③Designed To Help Strengthen The Immune System: Similac 360 Total Care is designed to

help strengthen baby’s immune system.

Similac Sensitive Infant Formula Reviews

Similac Sensitiveis an easy-to-digest, milk-based infant formula designed for sensitive tummies. It’s complete nutrition for fussiness, gas, or mild spit-up. Their formula has their exclusive blend of nutrients to help support baby’s brain and eye development.

Source:similac.com

Features:

①Designed For Baby’S Fussiness & Gas: Their sensitive formula for babies is specially designed

for fussiness and gas due to lactose sensitivity.

②Supports Brain & Eyes: Has DHA and lutein, important ingredients found in breast milk.

Similac Total Comfort Infant Formula Reviews

Similac Total Comfort formula is gentle on baby’s tummy; it has partially broken-down protein for easy digestion and prebiotics to support digestive health. It also contains their exclusive blend of ingredients to support baby’s brain and eye development. It’s a good choice for babies who have difficulty tolerating other milk-based formulas.

Source:similac.com

Features:

①Gentle Formula: Partially hydrolyzed whey protein allows for easy digestion.

②Digestive Health: Prebiotics to stimulate the growth of good bacteria to support digestive

health.

③Supports Brain & Eyes: Has DHA and lutein, important ingredients found in breast milk.

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Similac Advance vs. 360 Total Care vs. Sensitive vs. Total Comfort

Below, we will make a deep comparison between Similac Advance, 360 Total Care, Sensitive, and Total Comfort, so that you can purchase the one best for your baby.

1. At a Glance

	Advance	360 Total Care	Sensitive	Total Comfort
Price	$1.34 / oz	$1.62 / oz	$1.48 / oz	$1.42 / oz
Feeding needs	Everyday nutrition	Everyday nutrition	Fussiness & gas	Broken-down protein for easy digestion
Formula benefits	①Milk-based; ②Iron-fortified.	①Milk-based; ②Non-GMO; ③5 HMO Prebiotics.	①Milk-based; ②Disgned for baby's fussiness, gas, or mild spit-up.	①Broken-down protein for easy digestion; ②Prebiotics to support digestive health.
DHA	✔	✔	✔	✔
ARA	✔	✔	✔	✔
Choline	✔	✔	✔	✔
Inositol	✔	✔	✔	✔
Iron	✔	✔	✔	✔
Lactoferrin	×	×	×	×
MFGM	×	×	×	×
Prebiotics	×	✔	×	✔
Vitamin D	✔	✔	✔	✔
Not for infants or children with galactosemia.

2. Nutrients [Serving Size: 100 Cal (5 fl oz, prepared as directed)]

Amount per serving	Advance	360 Total Care	Sensitive	Total Comfort
Calories	100	100	100	100
Volume	148 mL	148 mL	148 mL	148 mL
Protein	2.07 g	2.07 g	2.1 g	2.32 g
Fat	5.6 g	5.6 g	5.4 g	5.4 g
Carbohydrate	10.7 g	10.5 g	10.9 g	10.7 g
Water	133 g	134 g	133 g	133 g
Linoleic Acid	1000 mg	1000 mg	1000 mg	1000 mg

Similac Total Comfort Infant Formula has the highest protein content.

3. Vitamins [Serving Size: 100 Cal (5 fl oz, prepared as directed)]

Amount per serving	Advance	360 Total Care	Sensitive	Total Comfort
Vitamin E	1.5 IU	1.5 IU	1.5 IU	1.5 IU
Vitamin K	8 mcg	8 mcg	8 mcg	8 mcg
Thiamin (Vitamin B1)	100 mcg	100 mcg	100 mcg	100 mcg
Riboflavin (Vitamin B2)	150 mcg	150 mcg	150 mcg	150 mcg
Vitamin B6	60 mcg	60 mcg	60 mcg	60 mcg
Vitamin B12	0.25 mcg	0.25 mcg	0.25 mcg	0.25 mcg
Niacin	1050 mcg	1050 mcg	1050 mcg	1050 mcg
Folic Acid (Folacin)	15 mcg	15 mcg	15 mcg	15 mcg
Pantothenic Acid	450 mcg	450 mcg	450 mcg	450 mcg
Biotin	4.4 mcg	4.4 mcg	4.4 mcg	4.4 mcg
Choline	24 mg	24 mg	24 mg	24 mg
Inositol	24 mg	24 mg	24 mg	24 mg
Vitamin C (Ascorbic Acid)	9 mg	9 mg	24 mg	24 mg
Vitamin A	300 IU	300 IU	300 IU	300 IU
Vitamin D	60 IU	60 IU	60 IU	60 IU

The vitamin content of these four Similac Infant Formulas is exactly the same.

4. Minerals [Serving Size: 100 Cal (5 fl oz, prepared as directed)]

Amount per serving	Advance	360 Total Care	Sensitive	Total Comfort
Calcium	78 mg	78 mg	84 mg	105 mg
Calcium	3.9 mEq	3.9 mEq	4.2 mEq	5.3 mEq
Phosphorus	42 mg	42 mg	56 mg	75 mg
Magnesium	6 mg	6 mg	6 mg	6 mg
Iron	1.8 mg	1.8 mg	1.8 mg	1.8 mg
Zinc	0.75 mg	0.75 mg	0.75 mg	0.75 mg
Manganese	5 mcg	5 mcg	5 mcg	5 mcg
Copper	90 mcg	90 mcg	90 mcg	90 mcg
Iodine	15 mcg	15 mcg	15 mcg	15 mcg
Selenium	2 mcg	2 mcg	2 mcg	2 mcg
Sodium	24 mg	24 mg	30 mg	44 mg
Sodium	1 mEq	1 mEq	1.3 mEq	1.9 mEq
Potassium	105 mg	105 mg	107 mg	118 mg
Potassium	2.7 mEq	2.7 mEq	2.7 mEq	3 mEq
Chloride	65 mg	65 mg	65 mg	65 mg
Chloride	1.8 mEq	1.8 mEq	1.8 mEq	1.8 mEq

The four Similac Infant Formulas differ only slightly in their mineral content.

5. Ingredients

①Similac Advance Infant Formula

Nonfat Milk, Lactose, High Oleic Safflower Oil, Whey Protein Concentrate, Soy Oil, Coconut Oil, Galactooligosaccharides*. Less than 2% of: Schizochytrium Sp. Oil†, M. Alpina Oil‡, Beta-Carotene, Lutein, Potassium Citrate, Calcium Carbonate, Ascorbic Acid, Soy Lecithin, Potassium Chloride, Magnesium Chloride, Ferrous Sulfate, Choline Bitartrate, Choline Chloride, Ascorbyl Palmitate, Salt, Taurine, Inositol, Zinc Sulfate, Mixed Tocopherols, d-Alpha-Tocopheryl Acetate, Niacinamide, Calcium Pantothenate, L-Carnitine, Vitamin A Palmitate, Copper Sulfate, Thiamine Hydrochloride, Riboflavin, Pyridoxine Hydrochloride, Folic Acid, Manganese Sulfate, Phylloquinone, Biotin, Sodium Selenate, Vitamin D3, Vitamin B12, Calcium Phosphate, Potassium Phosphate, Potassium Iodide, Potassium Hydroxide, and Nucleotides (Adenosine 5'-Monophosphate, Cytidine 5'-Monophosphate, Disodium Guanosine 5'-Monophosphate, Disodium Uridine 5'-Monophosphate).

* Prebiotic
† Source of DHA.
‡ Source of ARA.
Contains milk and soy ingredients.

Source:walmart.com

②Similac 360 Total Care Infant Formula

Nonfat Milk, Lactose, High Oleic Safflower Oil, Whey Protein Concentrate, Soy Oil, Coconut Oil, Human Milk Oligosaccharides (2'-Fucosyllactose, Lacto-N-Tetraose, 3-Fucosyllactose, 6'-Sialyllactose, 3'-Sialyllactose)*. Less than 2% of: Schizochytrium Sp. Oil†, M. Alpina Oil‡, Beta-Carotene, Lutein, Potassium Citrate, Calcium Carbonate, Ascorbic Acid, Soy Lecithin, Potassium Chloride, Magnesium Chloride, Ferrous Sulfate, Choline Bitartrate, Choline Chloride, Ascorbyl Palmitate, Salt, Taurine, Inositol, Zinc Sulfate, Mixed Tocopherols, d-Alpha-Tocopheryl Acetate, Niacinamide, Calcium Pantothenate, L-Carnitine, Vitamin A Palmitate, Copper Sulfate, Thiamine Hydrochloride, Riboflavin, Pyridoxine Hydrochloride, Folic Acid, Manganese Sulfate, Phylloquinone, Biotin, Sodium Selenate, Vitamin D3, Vitamin B12, Calcium Phosphate, Potassium Phosphate, Potassium Iodide, Potassium Hydroxide, and Nucleotides (Adenosine 5'-Monophosphate, Cytidine 5'-Monophosphate, Disodium Guanosine 5'-Monophosphate, Disodium Uridine 5'-Monophosphate).

* HMO, not from human milk.
† Source of DHA.
‡ Source of ARA.
Contains milk and soy ingredients.

Source:similac.com

③Similac Sensitive Infant Formula

Corn Syrup, Milk Protein Isolate, High Oleic Safflower Oil, Sugar, Soy Oil, Coconut Oil. Less than 2% of: C. Cohnii Oil*, M. Alpina Oil†, Short-chain Fructooligosaccharides, Beta-Carotene, Lutein, Potassium Chloride, Sodium Citrate, Calcium Phosphate, Potassium Citrate, Soy Lecithin, Magnesium Phosphate, Choline Chloride, Ascorbic Acid, Inositol, Ascorbyl Palmitate, Ferrous Sulfate, Taurine, Calcium Carbonate, Choline Bitartrate, Zinc Sulfate, L-Carnitine, Mixed Tocopherols, Niacinamide, d-Alpha-Tocopheryl Acetate, Calcium Pantothenate, Magnesium Chloride, Vitamin A Palmitate, Copper Sulfate, Thiamine Hydrochloride, Riboflavin, Pyridoxine Hydrochloride, Folic Acid, Potassium Iodide, Manganese Sulfate, Phylloquinone, Biotin, Sodium Selenate, Vitamin D3, Vitamin B12, Potassium Hydroxide, and Nucleotides (Adenosine 5'-Monophosphate, Cytidine 5'-Monophosphate, Disodium Guanosine 5'-Monophosphate, Disodium Uridine 5'-Monophosphate).

* Source of DHA.
† Source of ARA.
Contains milk ingredients.

Source:similac.com

④Similac Total Comfort Infant Formula

Corn Maltodextrin, Whey Protein Hydrolysate, High Oleic Safflower Oil, Sugar, Soy Oil, Coconut Oil. Less than 2% of: Schizochytrium Sp. Oil*, M. Alpina Oil†, Short-chain Fructooligosaccharides, Beta-Carotene, Lutein, Calcium Citrate, Potassium Phosphate, Calcium Phosphate, Potassium Hydroxide, Salt, Magnesium Chloride, Ascorbic Acid, Choline Chloride, Inositol, Potassium Chloride, Sodium Citrate, Calcium Hydroxide, Potassium Citrate, Ferrous Sulfate, Taurine, Choline Bitartrate, Zinc Sulfate, Ascorbyl Palmitate, L-Carnitine, Niacinamide, Mixed Tocopherols, d-Alpha-Tocopheryl Acetate, Calcium Pantothenate, Copper Sulfate, Vitamin A Palmitate, Thiamine Hydrochloride, Riboflavin, Pyridoxine Hydrochloride, Folic Acid, Manganese Sulfate, Potassium Iodide, Phylloquinone, Biotin, Sodium Selenate, Vitamin D3, Vitamin B12, and Nucleotides (Adenosine 5'-Monophosphate, Cytidine 5'-Monophosphate, Disodium Guanosine 5'-Monophosphate, Disodium Uridine 5'-Monophosphate).

* Source of DHA.
† Source of ARA.
Contains milk ingredients.

Source:target.com

6. Sizes

Similac Advance	Similac 360	Similac Sensitive	Similac Total Comfort
12.04 oz can 30.80 oz can	20.60 oz can 30.80 oz can	12.50 oz can 29.80 oz can	12.60 oz can

7. Verdict

Which product to choose mainly depends on the baby's situation and actual needs. Here are some suggestions for you:

Similac Advance is a nutritionally complete, milk-based, iron-fortified infant formula for baby’s first year. It has their exclusive blend of ingredients to support baby’s brain and eye development.
Similac 360 Total Care infant formula has an exclusive blend of 5 HMO prebiotics structurally identical to those in breast milk. It’s also nutrition designed for immune support, brain development & digestive health.
Similac Sensitive is an easy-to-digest, milk-based infant formula designed for sensitive tummies. It’s complete nutrition for fussiness, gas, or mild spit-up. Similac formula has their exclusive blend of ingredients to help support baby’s brain and eye development.
Similac Total Comfort formula is gentle on baby’s tummy; it has partially brokendown protein for easy digestion and prebiotics to support digestive health. It also contains our exclusive blend of ingredients to support baby’s brain and eye development.

Price: 360 Total Care＞Sensitive＞Total Comfort＞Advance

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