Top 8 Prescription Skincare Brands 2025

• Top Prescription Skincare Brands
  

| Curology

Curology is a personalized skincare brand founded by Dr. David Lortscher in 2014 and has made personalized skincare accessible in all 50 states. Curology believes that everyone deserves expert care and effective ingredients, which is why they make it easy to access clinically proven ingredients and science-backed treatments without any in-office visits or costly co-pays.

Curology offers traditional all-over topical treatments, cleansers, body washes, and even medicated pimple patches for spot treatment. Fill out an online questionnaire to outline your skin care goals and concerns like excessive oil, redness, or lack of firmness. You'll also be able to list any current medications and conditions that could interact with ingredients to ensure that your Curology product is the safest for you. 

Average Cost: A monthly treatment plan with Curology will roughly run you between $25-$60 per month, depending on your needs. Your initial month is also free, so you'll only have to pay the $4.95 shipping cost the first time around.

Pros:

Simple ordering from home

Low cost for prescription and nonprescription products

Free 30-day trial to test products

Easier access to prescription-only acne treatments

Cons:

Subscription required for prescription orders

The initial examination of the skin takes place only through photos and an online assessment

Shipping is only free for orders over $30

WHERE TO BUY: 

Curology (up to $10 cashback from Extrabux)

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| Agency 

Agency is a new personalized anti-aging skincare brand, brought to you by the founders of the buzzed-about brand Curology. The goal behind Agency Skincare is to offer anti-aging products that are customized for each person's unique skin with the help of the brand's licensed dermatology providers.

For patients, the Agency adventure begins by completing a questionnaire about their unique skin and medical histories, after which they upload three photos of their skin — one from the front, and two from each side of their face — via the brand's website. Once the photos are uploaded, patients are matched with one of Agency's licensed dermatology providers, who is one of the nearly 100 physicians, nurse practitioners, and physician assistants in-house at the company — no bots or algorithms involved.

PRICE RANGE: $30+/month

Pros:

Agency skincare ingredients are supported by research

Agency is cruelty-free

The online assessment and ordering is convenient

Easier access to prescription-only acne treatments

Cons:

No Agency skincare reviews

You must get a subscription to order Agency skincare products

The online assessment will not be as thorough as seeing a dermatologist in person

WHERE TO BUY: 

Agency Skincare (up to $5 cashback from Extrabux)

| Hers

Hers is part of Hims & Hers Health, Inc., an online therapy platform for women that provides care and prescriptions for anxiety, depression, birth control and more. Hers also offers consultations and treatment for some primary care conditions along with products for skin care, hair loss and non-prescription supplements to address a number of concerns. Hims & Hers is not designed to replace your in-person health care providers, rather supplement your care in cases of convenience if you don’t live near a health care provider or feel uncomfortable speaking in-person to a health care professional about your mental health.

Before getting started with Hers, you must create a profile and answer questions about your medical history, such as if you have chronic conditions like diabetes or high blood pressure, if you’ve had any surgeries, or if you're currently taking any medications. The platform asks questions about your health and the symptoms you’re experiencing that prompted you to reach out. You must have a government-issued ID and credit card to complete your profile. Your private information is encrypted and securely stored, according to the company.

Generic forms of common anxiety and depression medications start at $49 per month when you purchase a 3-month supply. When you first purchase the medication, the default at checkout is the 3-month supply for $49 per month. Hers offers a discount for your first order, bringing the first three months of a $49 prescription to $127. However, you’re charged the original amount after the first order. Shipping is free on all orders.

Pros:

Limited wait time: A medical professional will contact you within 24 hours.

You don't need insurance to receive a prescription 

Free shipping on medications and supplements

No in-person visits are required for a prescription

Cons:

You have to pay for three months' worth of prescriptions  upfront

Doesn't accept insurance: You'll have to pay out of pocket for all services and products provided

Little information on the website for pricing of subscriptions, services, and follow-ups

Not meant for people in an emergency mental health situation

WHERE TO BUY: 

Hers (up to $3 cashback from Extrabux)

Walgreens (up to 4% cashback from Extrabux

CVS (up to 2% cashback from Extrabux

| Nurx

Nurx is a telemedicine company that offers birth control, emergency contraception, skin care, and other sexual health treatments and tests. It markets itself as a female-focused company. It began business in 2015 and aims to offer affordable and convenient access to common medications and at-home health tests.

Unlike traditional doctor visits, you don't even need to leave home to receive your prescription. You complete your appointment virtually via a survey, and then your medications arrive at your doorstep with free shipping. 

Average Cost: Nurx offers a huge variety of treatments, so the cost is varied. The most expensive topical costs "as low as $35" per month out-of-pocket (it's cheaper if you have insurance), while the most expensive oral option runs as low as $40 per month.

Pros:

Makes healthcare more easily accessible

Cuts down on wait times for appointments and medication

Offers generic medication, including birth control pills

Offers skin care medications, including those for acne and rosacea

Provides personalized medication plans

Accepts copay and insurance

Cons:

Does not provide Accutane prescriptions for acne

Can take up to 72 hours to deliver prescriptions

Can be costly without insurance

WHERE TO BUY: 

Nurx

| Musely 

Launched in 2019 in Silicon Valley by four-time serial entrepreneur Jack Jia, Musely is the fastest-growing DTC telemedicine company specializing in treating skin conditions such as Melasma, hyperpigmentation, aging, and more, all with board certified dermatologists and proven prescription medications. 

Musely's branding centers on the fact that their products are "prescription skincare," which suggests that they contain more potent ingredients than OTC formulations. The brand claims that it "makes the science of youth accessible, affordable, and convenient," and brands their prescription skincare as "FaceRx."

Price: starts at $84 for three months.

Pros:

Users get a personalized treatment that targets their actual skin problem

You will have access to Musely eNurse which will help you know the progress of your treatment

There is a dermatologist available for any queries you may have during your treatment journey

No visiting the doctor or lining up at the pharmacist

Cons:

The products are available upon the doctor's approval

There is a doctor's visit fee

You might find the treatment pricy

WHERE TO BUY: 

Musely

| Ro

Ro is a direct-to-consumer telehealth company that offers a range of testing kits, prescriptions, and OTC products designed to address a variety of health issues.

After joining, you can complete a virtual visit with a licensed healthcare professional — such as a doctor or nurse practitioner — and receive a personalized treatment plan tailored to your needs.

You can also get prescribed medications delivered directly to your door in as little as 2 days. These medications are sent from the company's network of nationwide pharmacies.

Additionally, you can chat with a doctor, nurse, or coach on the Ro platform for free at any time to address any health concerns.

Pros:

Offers treatment plans for a wide range of health conditions

Offers a convenient and more accessible way to receive care

Provides both over-the-counter (OTC) and prescription treatments

Some products eligible for health savings account (HSA) or flexible spending account (FSA) reimbursement

Cons:

Products and services are not covered by insurance

May not be suitable for everyone

Some medications can be expensive

WHERE TO BUY: 

Ro

| Apostrophe 

Apostrophe is a revolutionary skincare prescription brand helping people around the world connect with dermatologists and get the right treatments easier than ever before. While its products also address concerns such as fine lines and wrinkles, melasma, and rosacea, its core offering is its anti-acne custom treatments with prescription-strength ingredients to treat even the most stubborn breakouts.

While Apostrophe does not have a mobile app, their site is quite mobile-friendly. It's attractive and intuitive interface took no time at all to navigate. You take and upload photos of your skin to your profile and this easy to do. A board-certified dermatologist, licensed in your state, will then review your photos and reach out to you via your site profile, prescribing your treatment plan. 

Custom products from Apostrophe include a wide range of some of the most effective acne-fighting ingredients on the market today, including oral medications. You can check in again with your assigned provider at semi-regular intervals, so if your skin changes, your formula/treatment option can change, too. If your primary concern isn't acne-related, Apostrophe might not check all the boxes for you.

Pros:

Clearly lists all ingredients on all custom products

Formulas adjust for skin and seasonal changes

Free shipping on all orders

Cons:

No serum formulas

Can be hard to pause deliveries

WHERE TO BUY: 

Apostrophe

| Dermatica

Dermatica, the personalised skin care platform, has undergone a brand makeover with an emphasis on providing affordable skin care solutions tailored to customers' needs. The online diagnosis platform made its debut in 2018, offering consumers tailored skin care advice and treatment plans to help tackle a variety of skin issues including acne, aging, pigmentation and rosacea.

Dermatica primarily addresses anti-aging concerns, but focuses on hyperpigmentation, melasma and acne as well. To use it, customers fill out an online questionnaire covering their skin issues, type and color; and upload photos for Dermatica’s doctors to analyze. The doctors recommend a combination of prescription ingredients to Dermatica's customers, and it acts as a compounding pharmacy to concoct them. Customers can employ an app to monitor their skin's progress and receive support from Dermatica's medical professionals.

Pros:

Users get a personalized treatment that targets their actual skin problem

The online assessment and ordering is convenient

No visiting the doctor or lining up at the pharmacist

Cons:

The products are available upon the doctor's approval

The online assessment will not be as thorough as seeing a dermatologist in person

WHERE TO BUY: 

Amazon

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