The Ordinary Multi-Peptide vs. Copper vs. Matrixyl vs. Argireline Serums: Differences and Reviews 2025

• About The Ordinary

Known for its reputation as an affordable yet highly effective skincare brand. The Ordinary is an evolving collection of treatments offering familiar, effective clinical technologies positioned to raise pricing and communication integrity in skincare. The brand was created to celebrate integrity in its most humble and true form. Its offering is pioneering, not in the familiar technologies it uses, but in its honesty and integrity. The Ordinary is born to disallow commodity to be disguised as ingenuity. The Ordinary is "Clinical formulations with integrity".

And each cutting-edge product they launch is 100% vegan and manufactured cruelty-free.An ideal choice for those looking to perfect their skincare routine, this brand has everything from facial serums to peels,toners and cleansers, all specifically catered to your skin type and your skin needs.

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• The Difference & Reviews

| The Ordinary Multi-Peptide + HA Serum

Sephora: $19.99/30ml (up to 5% cashback)

What Does It Do? 

The Ordinary 'Buffet' is now Multi-Peptide + HA Serum. Peptides this powerful deserve to be on the label. This universal formula combines a comprehensive array of technologies to improve skin smoothness and target multiple signs of aging at once. The Ordinary 'Buffet' is now Multi-Peptide + HA Serum. Peptides this powerful deserve to be on the label. This universal formula combines a comprehensive array of technologies to improve skin smoothness and target multiple signs of aging at once. By utilizing five well-studied peptide technologies, skin-friendly amino acids, and multiple hyaluronic acid complexes, it helps significantly improve the appearance of crow's feet, as well as improving the feel of skin elasticity and firmness.

Key Ingredients:

- Matrixyl™ 3000 Peptide Complex: Visibly reduces wrinkles and improves the look of elasticity, texture, and tone.

- Matrixyl™ Synthe'6™ Peptide Complex: Visibly reduces wrinkles and improves texture.

- ARGIRELOX™ Peptide Complex: Reduces the look of dynamic/expression wrinkles.

Best for: It's suitable for a wide range of skin types and ages, particularly those looking to address signs of aging such as fine lines, wrinkles, and loss of elasticity.

Texture & Fragrance: The colour is a little cloudy, and there´s a very slight smell to this. Multi-Peptide + HA consistency is on the thicker side, as you can see in the video below. Multi-Peptide + HA Serum can be a little sticky/tacky afterwards, but once you add another product or your moisturiser, it´s fine.

Review: This somewhat viscous clear face serum offers great hydration and a perfect glow to the skin. Since it dries sticky, can be used as a makeup primer as the foundation sticks to it easily. The Ordinary's Multi-Peptide + HA Serum is one of the best anti-aging serum with peptides. With three proprietary peptide complexes, it's a veritable powerhouse wrinkle serum – and one of the best anti-aging serums for the price. Strongly recommend it if your skin is dehydrated and you want that hydrated and juicy skin.

| The Ordinary Multi-Peptide + Copper Peptides 1% Serum

Selfridges: $32.50/30ml (up to 7% cashback)

What Is It?

Buffet + Copper Peptides 1% is now Multi-Peptide + Copper Peptides 1%! It is a universal formula which utilizes multiple skin support technologies that target multiple signs of aging at once. The formula incorporates five well-studied peptide technologies, skin-friendly amino acids, and multiple hyaluronic acids. For those looking for an all-in-one solution for skin care, Multi-Peptide + Copper Peptides 1% helps to improve the appearance of fine and dynamic lines and supports your skin's overall elasticity, smoothness and firmness. And because this advanced serum contains direct copper peptides, it also targets signs of aging that are typically associated with oxidative stress, resulting in radiant, healthier-looking skin.

Key ingredients: 

- Copper Peptides: Support a wide range of skin health functions like supporting normal immune function, collagen synthesis, fibroblast production, and anti-inflammatory responses.

- Matrixyl: Reduces the look of static and dynamic wrinkles.

- ARGIRELOX™: Targets the appearance of appearance of fine lines and wrinkles.

Best for: Those looking for an all-in-one solution for skin care, particularly those looking to address signs of aging such as fine lines, wrinkles, and loss of elasticity.

Texture & Fragrance: The serum's texture strikes the perfect balance between goopy and watery. It's slightly viscous and gel-like, but also lightweight. Upon application, it feels a bit thick on the skin and takes a minute to soak in, but once it's in, it's in without any pilling.

Perhaps the most disagreeable aspect of this serum is the scent. It has a sharp coppery scent that may not be for everyone. If you like to avoid scents, you might want to try a different peptide serum, but it's worth noting that there isn't any added fragrance if that's your main concern.

Review: The Ordinary's Multi-Peptide + Copper Peptides 1% is a beautiful serum. This is like a major suped up version with magical power of copper added in. It has a beautiful texture (slightly more fluid than the original) and a stunning blue colour. It sinks into the skin effortlessly, leaving it smooth and glowing.

It's significantly pricier than the brand's other products, falling more in line with a mid-tier or prestige price point.  If you're in the market for a science-backed serum that snatches up your skin, The Ordinary's Multi-Peptide + Copper Peptides 1% Serum might be your perfect match.

| The Ordinary Matrixyl 10% + HA

Sephora: $10.90/30ml (up to 4% cashback)

What Does It Do? 

Fight against the effects of ageing with The Ordinary Matrixyl 10% + HA, a concentrated skincare serum that combines Matrixyl 3000 with Matrixyl Synthe '6 to help support natural collagen synthesis and skin repair. This formula works to reduce the appearance of fine lines and wrinkles.

As well as its 10% concentration of matrixyl, the serum also uses hyaluronic acid to act as its delivery system. Not only does the inclusion of hyaluronic acid help to provide a plumping boost of hydration, but it also allows the matrixyl to penetrate deeper into the skin’s surface.

Key Ingredients:

- Matrixyl, Matrixyl 3000, and Matrixyl Synthe'6: Improve the look of fine lines and wrinkles.

- Hyaluronic Acid: Enhances the delivery of the Matrixyl, Matrixyl 3000, and Matrixyl Synthe'6.

Best for: All skin types and conscious skincare lovers, particularly those looking to reduce the appearance of wrinkles and promote a more youthful look.  

Texture & Fragrance: Like most The Ordinary products, the Matrixyl 10% + HA serum has a somewhat gel syrup-like consistency. It glides smoothly over the skin, allowing for maximum coverage while leaving the skin feeling hydrated and mildly moisturized.

The texture upon application can have a bit of a tacky feeling that is not sticky. When applied on dry skin, the serum is not as spreadable and can absorb rather quickly depending on how dry your skin is. It's not irritating at all and has no discernible scent. 

Review: It contains Matrixyl 3000 and Matrixyl Synthe'6. These powerful anti-wrinkle peptides work to provide the skin with long term anti-aging and skin smoothing benefits and are considered unparalleled in the industry. They boost collagen and elastin, reverse glycation damage (causes aging) and function to smooth and soften wrinkles from the inside out. If anti-aging is the main focus of your skincare routine then this ingredient is a must.

But, this is not designed for overnight effects, but for increased collagen production that helps slow down the bulldog cheeks that come with age. So if you have sensitivities or only want to add Matrixyl to your routine, the Matrixyl 10% + HA would be a good choice. And it's easy on the wallet. 

| The Ordinary Argireline Solution 10%

Cult Beauty: $12.70/30ml (up to 8% cashback)

What Does It Do? 

The Ordinary's 10% Argireline Solution is set to be your new youth-boosting best friend. Boasting a plumping and hydrating peptide compound, this lightweight treatment is designed to reduce the appearance of wrinkles. The potent formula also works hard to improve those fine, deep-set lines, especially around the eye area and forehead. The result? Smoother-looking skin.

Key Ingredients:

- Argireline Peptide Complex: Improves the appearance of facial areas prone to developing dynamic folds, including around the eyes and in the forehead area.

Best for: Dehydrated/dry and Oily skin (if you have open sores/acne then this may sting). It is more suitable for people with fine lines (not wrinkles).

Texture & Fragrance: The serum is clear, without any scent. This isn't a thick gel-like serum, but it is very, very watery. This is because Argireline seems to work best in a water-based formula. No film formers, yay! Because the texture is literally like water, though, you'll run through the bottle quickly. It's very easy to overapply. This is also formulated without any alcohol, silicones, and is vegan and cruelty-free.

Review: Argireline has been found to work exceptionally well for some people but not for others. The reason is there is some debate around whether Argireline in skincare products is actually capable of diffusing through the top layers of skin to reach the crucial muscle-nerve connections where it can take effect. The reason for this is thought to relate to the thickness of the dermis, meaning that younger, healthier skin is more resilient and has better barrier function, thereby keeping certain molecules out.  Older, thinker skin may be able to allow more of the molecule to pass through, therefore allowing the Argireline peptide to reach the areas where it can take effect.  

Conclusion

When comparing The Ordinary's Multi-Peptide, Copper, Matrixyl, and Argireline serums, the key difference lies in their targeted focus: Multi-Peptide aims to address multiple signs of aging with a blend of peptides, while Copper primarily focuses on skin repair and collagen production, Matrixyl targets wrinkle appearance by stimulating collagen synthesis, and Argireline specifically targets dynamic wrinkles caused by facial expressions; essentially, Multi-Peptide is a broader anti-aging solution, while the others tackle specific concerns with individual peptides. 

Breakdown:

Multi-Peptide Serum (aka "Buffet"):

Contains a combination of various peptides including Matrixyl, Argireline, and others, making it a versatile option to combat multiple signs of aging like fine lines, wrinkles, and loss of firmness. 

Copper Peptides Serum:

Features copper peptides which promote skin healing, collagen production, and have antioxidant properties, making it beneficial for acne scarring and overall skin health. 

Matrixyl Serum:

Primarily contains Matrixyl, a peptide known for stimulating collagen synthesis, making it particularly effective for addressing static wrinkles and improving skin elasticity. 

Argireline Serum:

Primarily contains Argireline, a peptide that mimics the effects of Botox by relaxing facial muscles, thus helping to diminish the appearance of expression lines around the eyes. 

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