5 Best Alternatives to Estee Lauder Advanced Night Repair Serum in 2025

• Best Alternatives to Estee Lauder Advanced Night Repair

| Missha Time Revolution Night Repair Ampoule 5X

Google Users Rating: 4.3/5

Walmart: $29.98 (up to 4% cashback)

Yesstyle: $36.50 (up to 4% cashback)

Stylevana: $24.09 (up to 3% cashback)

Time Revolution Night Repair Ampoule 5X is the fifth-generation of Missha's best-selling probiotic treatment! This upgrade is infused with even more Extreme Biome (77.2%), which is a combination of bifida ferment lysate and 10 other probiotics to deliver deep moisture and revive tired skin. This ampoule helps improve signs of aging by increasing skin elasticity, strengthening and firming skin, and evening out texture. Ingredients are fermented with Missha's EXTREME FERMENT α™ Method, a unique three-step fermentation method that stably delivers an extreme boost of active ingredients to the skin. 

Review: This serum is marketed to be the most close alternative to Estee Lauder ANR and has almost a similar ingredient list with a cheaper price tag.

MISSHA Night Repair Science Activator Ampoule closely mimics the ingredient list of its luxury counterpart, starting with its main ingredient, bifida ferment lysate. This yeast-derived product has proven anti-aging capabilities, from antioxidant benefits, to improving skin elasticity. The two twin serums also contain hyaluronic acid and skin conditioners like butylene glycol.

In fact, there are actually some instances where the Missha serum outshine's Estee Lauder's: for example, the Missha serum packs in more anti-aging ingredients including niacinamide, retinol, and nine additional ferments. This Advanced Night Repair alternative serum is incredibly similar in texture and is also designed to be used as part of your evening skincare routine, working hard overnight during the skin's recovery time to improve elasticity and reduce signs of aging.

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| Neogen Dermalogy Real Ferment Micro Serum

Google Users Rating: 4.6/5

LOOKFANTASTIC US: $28.50 (up to 10% cashback)

iHerb: $34.20 (up to 5% cashback)

Style Korean: $30.40 (up to 7% cashback)

With a formula that includes 61% fermented ingredients, Neogen Real Ferment Micro Serum is a gel-like serum that instantly absorbs into skin and infuses it with elasticity-improving bifida ferment lysate and saccharomyces ferment filtrate. The addition of betula alba juice provides antioxidant benefits while rice ferment filtrate brightens complexion and balances oil production. This real fermented micro serum helps improve skin's natural strength for firmer, brighter, and healthier looking skin.

Review: If you are more concerned about the skin barrier and skin health, this serum is more recommended. The key ingredient - Bifida Ferment Lysate is a probiotic ingredient that's used in one of the most iconic serums in the world, the Estee Lauder Advanced Night Repair. It potently protects against UV-induced damage in the skin and helps with DNA repair. The active ingredients like panthenol, collagen that quickly absorb into the skin to help reinforce skin elasticity while delivering instant hydration and skin radiance.

| Secret Key Multi Cell Night Repair Ampoule

Google Users Rating: 4.4/5

iHerb: $17.50 (up to 5% cashback)

Yesstyle: $16.80 (up to 4% cashback)

Style Korean: $15.00 (up to 7% cashback)

The Secret Key Multi Cell Night Repair is a highly concentrated serum (ampoule) that enhances the skin's resilience and keeps the skin hydrated and healthy. This Secret Key Multi Cell Night Repair Ampule is formulated with three types of plant-derived multi-cells, helps to improve your skin condition and keeps skin smooth. Manages your skin moisturized while you are in sleep. It has great texture with smooth and silky spreading feeling on to your skin. 

Review: This is a Korean Product and is also popularly known to be a cheaper alternative to Estee Lauder ANR. The Bifida Fermented Extract is known to improve skin's elasticity & protects the skin from damage! It is light weight as compared to Estee Lauder ANR and is non-sticky for the skin. It is also free from fragrance unlike Estee Lauder. It also contains niacinamide (brightening, collegen stimulating, calming) and three types of plant-derived multi-cells, which intensively nourish and moisturize overnight. 

| Isntree TW-Real Bifida Ampoule 

Google Users Rating: 4.7/5

Walmart: $20 (up to 4% cashback)

Yesstyle: $24.02 (up to 4% cashback)

Stylevana: $15.89 (up to 3% cashback)

Revive aging or damaged skin with this potent ampoule infused with 88% bifida ferment lysate and three kinds of peptide to strengthen the skin barrier while improving its elasticity. Additional ingredients of pumpkin ferment extract, soybean ferment extract and rice ferment filtrate further protect skin from external aggressors. This also contains niacinamide to improve the tone and barrier.

Review: The Isntree TW-Real Bifida ampoule is a good alternative to the pricey Estee Lauder Advanced Night repair serum. It has way more amazing ingredients list than the Estee Lauder advanced night repair serum with just a fraction of its price. While it may not have as many probiotics as some of the other Estee Lauder alternatives, this ampoule has additional anti-aging technologies, thanks to the peptides in the formula. It is lightweight and how it can easily gets absorbed by the skin plus it leaves your skin hydrated and radiant.

| Manyo Factory Bifida Biome Complex Ampoule

Google Users Rating: 4.7/5

Yesstyle: $36.30 (up to 4% cashback)

Stylevana: $36.29 (up to 3% cashback)

Amazon: $31.50

The Bifida Biome Complex Ampoule from Manyo Facotry replenishes and balances skin for a more youthful looking complexion. The highly concentrated formula leaves sensitive skin revived and radiant. Patented ingredient, Bifida Biome™, along with 5 types of probiotics balance skin's microbiome. They help fortify the skin barrier to protect from external aggressors and to keep moisture in, evening out tone and texture and brightening complexion. 10 types of hyaluronic acid effectively penetrate different layers of the skin for deeper hydration that plumps up skin.

Review: This Advanced Night Repair alternative is formulated to replenish the outer layer of the skin and reduce the appearance of wrinkles and fine lines, like Advanced Night Repair. The ampoule uses Manyo's patented Bifida Biome complex to improve the condition of your skin. Like Advanced Night Repair, this ampoule contains squalane to moisturize and protect the skin and caffeine to revitalize the skin and improve skin tone. It has a lightweight, non-greasy texture similar to Estee Lauder and feels very moisturizing on the skin. The fragrance-free serum has hydrating and barrier repair properties making it ideal for dry and sensitive skin types.

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