Top 10 Medical-Grade Skincare Brands that Dermatologists Recommend 2025

• The Best Medical-Grade Skincare Brands

| SkinCeuticals 

When looking out for top professional skin care lines for estheticians, SkinCeuticals skincare is one of the best in show. SkinCeuticals was born from decades of skin cancer research that led to pivotal breakthroughs in antioxidants. 

From potent Vitamin C antioxidant serums to sunscreens to multi-purpose cleaners and nourishing moisturizers, SkinCeuticals skin care products are designed to improve skin's health and prevent future skin conditions. SkinCeuticals skin care is based on the principles of prevention, protection and correction. Each skin care product has proven scientific support to help maintain and improve skin health. 

Star Products: SkinCeuticals C E Ferulic

Shop Stores: 

SkinCeuticals (up to 6% cashback from Extrabux)

SkinStore (up to 8% cashback from Extrabux)

LOOKFANTASTIC UK (up to 10% cashback from Extrabux)

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| SkinMedica 

Whatever your skin care needs or challenges may be, you deserve healthier looking skin. SkinMedica® has dedicated nearly two decades of research to formulating advanced products that promote the long-term health of your skin. SkinMedica products work with your skin's natural healing properties to help you achieve transformative results from the inside out.

They are most known for their revolutionary anti-aging growth factor, TNS, which can be found in some of their most popular products. All products that they offer lead to better looking, younger, and healthier skin. These superior products utilize rejuvenators such as vitamins E and C, retinol, tea tree oil, and salicylic acid.

Star Products: SkinMedica TNS Essential Serum

Shop Stores: 

Dermstore (up to 7% cashback from Extrabux)

SkinStore (up to 8% cashback from Extrabux)

Walmart (up to 4% cashback from Extrabux)

| Obagi 

With a 30-year legacy of science and innovation, Obagi has led the way in creating inclusive products that meet the needs of every skin tone and type. They believe that skin care is more than correcting or preventing – it's about developing scientifically-backed, clinical-quality formulations that promote healthy skin into the future. All ages. All skin types.

The Obagi skin care system is divided into multiple categories in order to perfect specific skin conditions, helping to discover more radiant skin. These skin care systems include Obagi CLENziderm, the Obagi Nu-Derm system, the Obagi Elastiderm line, and the Obagi Professional-C Serum. The Obagi Nu-Derm cleanser is part of an anti aging system that transforms cellular functions to keep skin looking flawless. The results from using Obagi skin care systems is beautiful healthy skin that is smooth and tight, even in skin tone, free of disease and sensitivity, naturally hydrated and functioning properly to fight disease and signs of aging. Obagi products address the skin in its totality.

Star Products: Obagi Professional-C Serum 20%

Shop Stores: 

Dermstore (up to 7% cashback from Extrabux)

SkinStore (up to 8% cashback from Extrabux)

SkinCareRX 

| PCA Skin 

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Founded by an aesthetician and developed by the dermatology community, PCA SKIN is a results-driven skincare company with advanced formulas for challenging skin concerns.

PCA SKIN is a leading innovator in the development of highly effective professional treatments and daily care products. Their vision is to improve people’s lives by providing results-oriented skin care solutions for the health of your unique skin. PCA SKIN pairs leading professional treatments with advanced daily care to provide effective solutions to all skin concerns: aging, acne, discoloration, sensitive skin, and preventative care. 

Star Products: PCA Skin Hyaluronic Acid Boosting Serum

Shop Stores: 

Dermstore (up to 7% cashback from Extrabux)

SkinStore (up to 8% cashback from Extrabux)

LOOKFANTASTIC US (up to 10% cashback from Extrabux)

| iS Clinical

iS Clinical has carefully assembled a team of world-renowned pharmacologists and physicians who are responsible for some of the greatest advances in skin care and anti-aging medicine. Together their knowledge and expertise has created a line of skincare products that target some of the most challenging skin problems such as acne, rosacea, aging skin, pigment changes and dry, moisture-starved skin.

The brand's skincare ethos comprises four steps: cleanse, treat, hydrate and protect, and the range offers products in each category for a variety of specific skin types. High-grade ingredients – think plant-derived acids, vitamins A to E, stem cells and ceramides – are combined to deliver the most notable results in the least amount of time. 

Star Products: iS Clinical Active Serum

Shop Store: 

Dermstore (up to 7% cashback from Extrabux)

SkinStore (up to 8% cashback from Extrabux)

LOOKFANTASTIC US (up to 10% cashback from Extrabux)

| Dr. Dennis Gross 

Founded by Dr. Dennis Gross, Dr Dennis Gross Skincare is a skincare brand designed to offer the highest performance possible while meeting the highest safety standards. Inspired by the harsh effects of chemical peels, Dr. Gross wanted to create a clean, gentle formula that offered superior results without irritation. That's why the brand's formulations use only pharmaceutical-grade ingredients, which are free from parabens, sulphates, and phthalates.

Initially, Dr Dennis Gross Skincare launched with one product – an at-home peel. Today, the brand has expanded to include a wide range of skincare products, from serums and cleansers to moisturizers and sunscreen. These products address numerous concerns, including acne, dark spots, blemishes, deep wrinkles, and fine lines.

Star Products: Dr. Dennis Gross Skincare Alpha Beta Extra Strength Daily Peel

Shop Stores: 

Sephora (up to 4% cashback from Extrabux)

Dermstore (up to 7% cashback from Extrabux)

SkinStore (up to 8% cashback from Extrabux)

| Lancer Skincare 

Lancer helps achieve results with their line of carefully researched anti-aging skincare products. You might have heard of The Lancer Method, a three step exfoliation, cleansing, and moisturizing process created by celebrity dermatologist Dr. Harold Lancer that works to improve skin tone and texture. 

And while exfoliating every day before you cleanse may seem like a big no-no, Dr. Lancer claims that this physical manipulation of the skin activates the dermis to activate skin cell turnover, which gets sluggish as we age. It also allows for a deeper cleanse and more efficient delivery of active ingredients. Although the Lancer Method is the cornerstone of the brand, Lancer Skincare offers a variety of serums, creams, peels, and oils to address all skin concerns, regardless of skin type. 

Star Products: Lancer Skincare Omega Hydrating Oil

Shop Stores: 

Lancer Skincare (up to 9.5% cashback from Extrabux)

Dermstore (up to 7% cashback from Extrabux)

QVC (up to 4% cashback from Extrabux)

| CosMedix

CosMedix offers a unique advantage to your skin care regimen: Chiral Correction. Molecules, the building blocks of nature, come in two forms: left-oriented and right oriented. By using the same percentage of each (Chiral Correction), CosMedix offers highly efficacious products. Leftover molecules act as free radicals, which means many products claiming to be antioxidants are causing as much harm as good.

In addition to being the market's foremost chirally correct skin care brand, CosMedix is a plant-based, earth-friendly line, free of artificial colors and preservatives.

CosMedix believes you don't need harsh chemicals to enhance the beauty of your skin or improve the appearance of skin troubled by conditions like acne, rosacea or excessive sun damage. Their products are formulated with some of the most advanced skin care ingredients available including peptides and growth factors, many of which are plant-based. This makes the CosMedix safe and effective even for sensitive skin. 

Star Products: Cosmedix Opti Crystal Liquid Crystal Eye Serum

Shop Stores: 

Dermstore (up to 7% cashback from Extrabux)

SkinStore (up to 8% cashback from Extrabux)

Walmart (up to 4% cashback from Extrabux)

| Neocutis 

Founded in 2003, Neocutis is a specialty biopharmaceutical company that delivers breakthrough anti-aging skin treatments. NeoCutis' products promote the growth of new skin, speeding the healing of cuts and burns while simultaneously eliminating the process that leads to scarring.

The brand prides itself on its exclusive Swiss technology, which includes all manner of patented ingredients, including MPC, a Micro Protein Complex that nourishes and promotes the production of collagen, elastin and hyaluronic acid within the skin.

Star Products: Neocutis Lumiere Illuminating Eye Cream

Shop Stores: 

Dermstore (up to 7% cashback from Extrabux)

SkinStore (up to 8% cashback from Extrabux)

Walmart (up to 4% cashback from Extrabux)

| Epionce 

Developed by practicing dermatologist Dr. Carl R. Thornfeldt, Epionce is rooted in science and integrates over 20 years of clinical skin research into its formulations. Founded in 2002, Epionce is one of the most highly effective non-prescription skin care lines on the market today. Their philosophy is simple: healthy skin is beautiful skin.

Backed by scientific research, Epionce products feature unique therapeutic and patent-pending formulations. Powerful ingredients work to strengthen the skin's natural defenses while repairing and restoring damaged areas. Their results-driven line specifically works to help delay and reverse aging and targets conditions such as acne, dermatitis, eczema and psoriasis.

Star Products: Epionce Renewal Facial Cream

Shop Stores: 

Dermstore (up to 7% cashback from Extrabux)

SkinStore (up to 8% cashback from Extrabux)

SkinCareRX

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