8 Best Anti-aging Serum Capsules and Ampoules for Lines & Wrinkles in 2025

• The Best Anti-aging Serum Capsules and Ampoules

| Elizabeth Arden Retinol Ceramide Line Erasing Night Serum Capsules

($51/30-piece, up to 8% cashback at Elizabeth Arden)

Improve the appearance of skin with Elizabeth Arden Retinol Ceramide Capsules Line Erasing Night Serum, an encapsulated Retinol formula that targets signs of aging to promote smoother, younger-looking skin. 

Each is 76% more potent that unencapsulated retinol. Ceramides help replenish skin's natural ceramides to reinforce skin's moisture barrier; retinol enhances skin's natural collagen to visibly reduce lines and wrinkles; and youth-restoring peptides promote wrinkle-smoothing and improve the appearance of skin tone and elasticity. Avocado, sunflower seed and olive oils deliver moisturizing and skin conditioning benefits.

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| RoC Retinol Correxion Line Smoothing Night Serum Capsules

($32.99, up to 7% cashback at RoC Skincare)

Support healthy collagen with RoC Retinol Correxion Line Smoothing Night Serum Capsules. Made with a high concentration of pure RoC® Retinol and Antioxidants, the serum is sealed tight in a capsule for optimal Retinol freshness and potency. Each capsule is designed to rival prescription skincare without the irritation; 100% of testers had 0% irritation. Clinically proven to revitalize skin while you sleep.

| Eve Lom Age-Defying Smoothing Treatment

($150, up to 8% cashback at SkinStore)

The Eve Lom Age Defying Smoothing Treatment is a potent anti-ageing serum contained within a capsule to maximise freshness. 

The capsules contain active anti-wrinkle cosmetic ingredients that work with amino acid combinations to form a hexapeptide, working together in combatting signs of ageing. Eve Lom Age Defying Smooth Treatment also includes tocotrienol, an antioxidant that is part of the vitamin E family, which helps to protect the skin from damage caused by free radicals and harmful rays from the sun.

| Darphin Ideal Resource Youth Retinol Oil Concentrate

($98, up to 6% cashback at Darphin)

Unveil a brighter and smoother looking complexion with the Darphin Ideal Resource Youth Retinol Oil Concentrate, an anti-ageing skincare treatment dispensed in capsule form.

Blending botanical-boosted Retinol with nourishing Jojoba Oil, each capsule works to reduce the appearance of lines and wrinkles while improving radiance and tone. The powerful anti-ageing concentrate delivers a plumping and rejuvenating effect to encourage a youthful-looking visage. Retinol is best applied at night, as it supports the skin during its natural repair and regeneration mode, which includes the making of new collagen.

| Estée Lauder Advanced Night Repair Intensive Recovery Ampoules 

($104, up to 3% cashback at Harrods)

These powerful little pods are filled with a precision dose of nourishing treatment oil that helps skin address the irritation that can cause premature signs of aging. Its active formula includes ChronoluxAI technology, which helps reduce visible irritation and supports skin's natural synchronization. They also support skin's natural ability to repair its appearance at night, and help skin strengthen its resistance against future assaults.

| L'Oreal Revitalift Derm Intensives Hyaluronic Acid Ampoules

($19.99, up to 4% cashback at Walgreens)

As we age, our skin's hyaluronic acid production decreases, causing signs of aging.

Dermatologist-validated, L'Oréal's Revitalift Derm Intensives 1.9% Pure Hyaluronic Acid Replumping Ampoules give you 7 doses of pure Hyaluronic Acid to visibly plump skin. Each individual ampoule contains an optimal amount of Hyaluronic Acid to hydrate your skin. After 1 ampoule, skin looks visibly smoother and instantly feels hydrated. After 7 ampoules, skin looks healthier, replumped, and wrinkles are visibly reduced.

| Vichy LiftActiv Peptide-C Anti Aging Ampoule Serum

($29.5, up to 10% cashback at Vichy)

During life's stressful moments, Supercharge Your Skin with LiftActiv Peptide-C Anti-Aging Ampoules to visibly reduce wrinkles in one month and firm skin from the first use. 

This anti-wrinkle ampoule is enriched with 10% Vitamin C, natural-origin hyaluronic acid and peptides. The concentrated formula targets fine lines and wrinkles, lack of firmness and boosts skin radiance, whilst being tightly sealed in a glass ampoule to ensure optimal freshness and clinically proven efficacy.

| Dr Barbara Sturm Hyaluronic Ampoules

($145, up to 4% cashback at Sephora)

This ampoule includes both long and short chain hyaluronic molecules for visibly healthier skin. It also contains purslane for its anti-inflammatory and antioxidant benefits as well as other active ingredients that soothe and smooth the skin.
Use of this intense moisturiser will help create firmer skin, reducing the appearance of fine lines, with regular use helping to prevent new wrinkles from appearing.

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