8 Best Squalane Skincare Products for Hydrated Skin 2025

• What is Squalane?

Squalane is a hydrocarbon derived by hydrogenation of squalene, a naturally hydrating lipid (or fat) produced by the sebaceous (or oil) glands in our skin.  As we get older, our bodies produce less and less squalene – which is where squalane comes in. Put simply, it's an oil that helps replenish skin's natural moisture.

Historically, squalane was harvested from shark's livers, but most modern formulas are now derived from plants including olives, rice bran or sugarcane. 

• Benefits of Squalane for Skin

Hydrated skin is healthy skin. So, when applied topically, squalane has tremendous benefits.

Justifiably hailed as a hero product for hydration, squalane locks in moisture, acts as a detoxifier to boost collagen production, and generally results in a smoother, more vibrant and complexion.

Research shows it also has anti-inflammatory properties which can reduce redness and swelling, and can help protect skin from UV damage. 

• The Best Squalane Skincare Products

| The Ordinary 100% Plant-Derived Squalane

($7.90, up to 4% cashback at Sephora)

The Ordinary 100% Plant-Derived Squalane is an exceptional hydrator and can prevent ongoing loss of hydration that impairs dermal suppleness. Squalane is non-comedogenic and is suitable for use on all skin types. It can also be applied to hair to increase heat protection, add shine and reduce breakage potential.

| Biossance 100% Squalane Oil 

($34.00, up to 4% cashback at Sephora)

A weightless and replenishing multipurpose squalane oil—harvested from renewable sugarcane—that’s highly stable and totally sustainable. Designed to mimic squalene - a natural molecule present in our skin that diminishes over time – this moisturising ingredient comes from 100% plant-based, renewable sugarcane and enhances elasticity as well as protecting your skin. 

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| Kiehl's Ultra Facial Cream

($32, up to 8% cashback at Kiehl's)

Get the ultimate in hydration from Kiehl's Ultra Facial Cream, a unique blend of ingredients combined to create the ideal moisturiser. Formulated with Glacial Glycoprotein and olive-derived Squalane, this beloved moisturizer helps strengthen skin's barrier and leaves skin feeling comfortable and well-balanced. With an ultra-lightweight texture, this facial cream absorbs easily for softer, smoother, healthier-looking skin. 

| First Aid Beauty Skin Rescue Daily Face Cream

($20, up to 10% cashback at LOOKFANTASTIC US)

This gentle moisturizer helps keep skin feeling comfortably supple and protected. The oil-free formulation includes a blend of moisturizing ceramides and squalane to help hydrate and smooth skin's appearance. The formula is also infused with the FAB Antioxidant Booster, a powerful botanical blend of white tea, licorice root, and feverfew extracts, to help combat environmental aggressors.

| The Inkey List Squalane Oil

($11.99, up to 4% cashback at Sephora)

Hydrate and balance your skin with The INKEY List Squalane Face Oil. 100% plant-derived, this Squalane oil is lightweight, non-greasy oil that's superhydrating for healthy, glowing skin. It can also help to reduce the appearance of fine lines and support oil control. So it's a great choice for all skin types, from dry to oily skin.

| Tata Harper Beautifying Face Oil

($98, up to 8% cashback at Tata Harper)

Tata Harper's Beautifying Face Oil is enriched with 17 active ingredients including organic Olive Oil and Camellia Seed Oil to revitalize your complexion. Lightweight and fast-absorbing, it's formulated with Squalane, a non-comedogenic compound that leaves skin feeling hydrated, plump and soft. It's also completely natural and suitable for all skin types.

| Peter Thomas Roth Oiless Oil 100% Purified Squalane

($38, up to 8% cashback at SkinStore)

Oilless Oil™ 100% Purified Squalane is for anyone looking for all the benefits of an oil without leaving an oily or greasy after-feel. Formulated with squalane that is derived from sustainable sugar cane, it penetrates deep into your skin to provide intensive hydration that absorbs quickly, yet still allows your skin to breathe. As well as being left nourished, your skin will also have improved elasticity for a firmer, smoother and more youthful-looking complexion. 

| Indie Lee Squalane Facial Oil

($34, up to 4% cashback at Sephora)

Made with 100% olive-derived squalane, this weightless facial oil hydrates the skin without clogging pores or leaving behind a heavy, greasy finish.  It worked well to balance out our skin, both reducing breakouts and redness and improving the condition of dry patches. Ideal for all skin types.

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