6 Natural Supplements to Strengthen Kidney and Liver 2025

1. Milk Thistle

Milk thistle is a plant that is native to Europe and was brought to North America by early colonists. Milk thistle is now found throughout the eastern United States, California, South America, Africa, Australia, and Asia. The above ground parts and seeds are used to make medicine. This herb has been used in medicine for thousands of years. Records show first-century Romans used it for liver health. The active ingredient in milk thistle that helps your kidneys and liver is called silymarin.

What Does Milk Thistle Do For the Liver?

Milk thistle is taken by mouth most often for liver disorders, including liver damage caused by chemicals, alcohol, and chemotherapy, as well as liver damage caused by Amanita mushroom poisoning, nonalcoholic fatty liver disease, chronic inflammatory liver disease, cirrhosis of the liver, and chronic hepatitis. It helps to:

• Reduce inflammation

• Stabilize membranes in the liver

• Increase glutathione production

• Boost superoxide dismutase

• Decrease liver tumor cell division

Some people apply milk thistle directly to the skin for skin damage caused by radiation.

Although more research is needed on how it works, milk thistle is thought to reduce damage to the liver caused by free radicals, which are produced when your liver metabolizes toxic substances.

One study also found that it may slightly extend the life expectancy of people with cirrhosis of the liver due to alcoholic liver disease.

Although milk thistle extract is commonly used as a complementary therapy for people with liver diseases, there’s currently no evidence that it can prevent you from getting these conditions, especially if you have an unhealthy lifestyle.

What Does Milk Thistle Do For the Kidney?

Regarding the kidneys, milk thistle's effects on them 'closely mirror the herb's effects on the liver,' and intriguing clinical research shows normalized thiol status in patients with end-stage diabetic nephropathy, and in others receiving ambulatory peritoneal dialysis, with milk thistle treatment. Silymarin stimulates protein synthesis and cell regeneration in the kidneys just as in the liver. 

Silymarin has been observed to have a moderate diuretic effect in isotonic saline-loaded rats; however, there was also a marked decrease in potassium excretion, suggesting that it is a potassium-sparing diuretic. 

Abascal and Yarnell recommend the use of milk thistle with any potentially kidney-damaging drug or treatment, as well as for patients with acute tubular necrosis or other situations involving acute epithelial cell loss.

Milk thistle has very similar effects on your two detox organs. It’s a top pick for natural kidney and liver detox.

1. Puritan's Pride Milk Thistle 1000 mg 4:1 Extract (Silymarin) for $13.99

Where to Buy Products of Puritan's Pride?

You can go Puritan's Pride Official Website, and don't forget to sign up at Extrabux (What is Extrabux?) , then you can get 4% super cashback from Extrabux! Sign-Up Bonus: Free to join it & get $20 welcome bonus!

2. Nature's Bounty, Milk Thistle, 250 mg, 200 Capsules for $20.98

Where to Buy Products of Nature's Bounty?

You can go iHerb Official Website through Extrabux, then you can get 4% super cashback .

3. Now Foods, Silymarin, Milk Thistle Extract, 300 mg, 100 Veg Capsules for $12.48

4. Life Extension Advanced Milk Thistle for $33

Where to Buy Products of Life Extension?

You can go Life Extension Official Website through Extrabux, then you can get 8% super cashback .

5. GNC HERBAL PLUS® MILK THISTLE 1300 MG for $26.99

Where to Buy Products of GNC?

You can go GNC Official Website through Extrabux . Cashback temporarily unavailable. 

2. Marshmallow Root

Marshmallow Root (Althaea officinalis) is a perennial herb that’s native to Europe, Western Asia, and Northern Africa. It’s been used as a folk remedy for thousands of years to treat digestive, respiratory, and skin conditions. Fortunately, this herb does helpful things for your kidneys and liver.

What Does Marshmallow Root Do For The Kidneys?

When it comes to protecting the body, a discussion involving the best ways of keeping the heart, brain, and digestive tract strong is almost always brought up. The urinary tract – which includes the kidneys and bladder – carries a heavy burden when it comes to removing many of the body’s toxins. When the urinary tract is under a great deal of stress, toxins can build up and damage organs. 

Marshmallow root is a demulcent, hence it relieves inflammation and helps soothe mucous membranes to ease passage of kidney stones. One of best herbs to use for kidney problems, it is soothing and healing to inflamed tissue. Up to a quart of marshmallow tea can be taken per day. Herbalists have reported improvement in symptoms of a variety of kidney problems with this herb used in this way. Combined with Uva Ursi, it can help heal urinary tract infections.

What Does Marshmallow Root Do For The Liver?

Marshmallow root is an herbal remedy that can treat colds and reduce its symptoms including coughs and sore throat, improve bronchitis, skin irritation and asthma. Marshmallow roots are a powerful anti-inflammatory that can also improve kidney and liver function, digestion and arthritis.

Your liver bile ducts can become damaged over time. Marshmallow root acts to soothe this damage. In fact, it stimulates the production of epithelial cells. These are the cells that line the inside of your organs and ducts. Having a strong, healthy bile duct can better help your liver detox.

One additional benefit from marshmallow is its ability to bind to heavy metals. Binding heavy metals and ushering them out of your body before they can create damage is another reason to love this root for liver and kidney detox.

1. Nature's Way, Marshmallow Root, 960 mg, 100 Vegan Capsules for $10.99

2. Oregon's Wild Harvest, Marshmallow, 90 Gelatin Capsules for $13.45

3. Parsley

Parsley is a popular herb often used in American, European, and Middle Eastern cooking. It’s commonly used to elevate the flavor of dishes like soups, salads, and fish recipes. Aside from its many culinary uses, parsley is highly nutritious and has been shown to have many powerful health benefits. It is full of flavonoids, vitamins, minerals, and antioxidants. Parsley has some powerful kidney health and liver detox properties you can take advantage of.

What Does Parsley Do For The Kidneys?

Parsley has also been shown to act as a natural diuretic, which can increase urination and prevent kidney stone formation.

Parsley has also been shown to have anti-inflammatory properties due to its antioxidants, including flavonoids, carotenoids, and vitamin C.

Additionally, parsley may help keep your kidneys healthy by reducing high blood pressure, a major risk factor for kidney disease.

Parsley is high in nitrates that help dilate blood vessels, which improves blood flow and lowers high blood pressure. Research indicates that nitrate-rich foods like parsley can help maintain healthy blood pressure levels.

The anti-inflammatory properties of parsley, along with its ability to regulate urinary pH and reduce blood pressure, may help keep your kidneys healthy and lower your risk of kidney stones.

What Does Parsley Do For The Liver?

Parsley acts as a natural diuretic. Your urine is a route through which toxins are expelled from your body, so incorporating parsley to help this natural process along may prove useful for cleansing. Parsley also helps to produce glutathione, which helps protect your liver from damage. 

Parsley can also lower your high blood glucose levels, which can inflame the liver when they are too high. It can help protect your liver by reducing inflammatory liver enzymes. 

Similarly to marshmallow, parsley can help to bind onto and remove heavy metals from your body.

Parsley’s diuretic and protective roles make it an especially useful kidney detox herb that also has benefits for your liver!

1. Nature's Way Parsley Leaf 450 mg for $7.79

2. Organic Parsley Leaf Tea, 18 Bleach-Free Tea Bags for $9.15

4. Gynostemma

Gynostemma (Jiaogulan) is a plant that grows wild in parts of Asia. The leaf is used to make medicine. Jiaogulan is sometimes referred to as "Southern Ginseng" because it grows primarily in south central China and is used in similar ways as ginseng.

People commonly use jiaogulan by mouth for high cholesterol, diabetes, liver disease, obesity, and many other conditions. It can also improve your liver and kidney detox process.

What Does Gynostemma Do For The Kidneys?

When your organs get injured from exposure to toxins, a process called fibrosis can occur. In fibrosis, cells create scar tissue instead of healthy tissue. Scar tissue doesn’t function like healthy tissue and inhibits the kidney's ability to detox optimally. High levels of fibrosis can lead to chronic kidney disease or the loss of kidney function altogether. Gynostemma can influence the genes in your kidneys to help produce healthy, well-functioning tissue and reduce fibrosis. 

What Does Gynostemma Do For The Liver?

Gynostemma extract may support healthy liver function in a variety of diseases.In a clinical trial on 56 people with non-alcoholic fatty liver disease, gynostemma extract (as an add-on to conventional therapy) reduced liver cell death (liver damage markers AST and ALP), body mass index, and insulin resistance.

Similarly, gynostemma supplementation reduced liver fat accumulation and liver cell death in animal models of non-alcoholic fatty liver disease. Treatment with gynostemma improved liver cell survival in animal models of chronic liver injury.

It also influences the genes involved in liver cancer cell growth and has been shown to inhibit cancer cell multiplication, which would help protect you from liver cancer. 

Gynostemma is a potent anti-inflammatory for the intestines as well. The intestines are the next step in your liver detox. The liver dumps toxins into this part of your drainage system to be taken from the body. Gynostemma does triple duty by helping your kidneys, liver, and intestines. This makes it a favorite to enhance your natural detox. 

1. Paradise Herbs Jiaogulan 250 mg 12:1 Extract for $9.99

2. Paradise Herbs, Jiaogulan, 60 Vegetarian Capsules for $9.99

3. Solaray, Jiaogulan Root Extract, 410 mg, 60 VegCaps for $13.45

5. Beetroot

Beetroots, commonly known as beets, are a popular root vegetable used in many cuisines around the world. Beets are packed with essential vitamins, minerals and plant compounds, some of which have medicinal properties. They’ve been eaten for thousands of years because of their health benefits. Beets were found in Egyptian pyramids dating back to the Third Dynasty. Even without knowing it, by consuming beets, they were helping their liver and kidneys detox.

What Does Beetroot Do For The Kidneys?

Beetroot can enhance your production of nitric oxide. Nitric oxide dilates blood vessels, which increases blood flow. This additional blood flow can help your kidneys work better than when blood flow is restricted.

The bright red pigment of beetroot is called betanin. It can help reduce inflammation and oxidative stress. It may also help protect your kidneys from damage. 

Beetroot can also help protect your kidneys from being injured from antibiotics, which can sometimes cause the failure of these essential organs. It helps to increase catalase, your body's natural in-house antioxidant, which is crucial for effective kidney function and detox. Beetroot helps you to downregulate pro-inflammatory substances in the kidneys as well.

What Does Beetroot Do For The Liver?

Beetroot juice contains antioxidants, vitamin A, vitamin B-6, and iron. These compounds help protect the liver from inflammation and oxidative stress while enhancing its ability to remove toxins from the body.

A recent small-scale animal study in rats with liver injury found that the rodents that received a beetroot extract had minimal liver damage in comparison with control rats.

1. Puritan's Pride Beet Root Extract 500mg for $7.74

2. GNC SUPERFOODS BEET ROOT for $14.99

3. Nature's Way Beet Root for $6.28

6. Ginger

People have used ginger in cooking and medicine since ancient times. It is a popular home remedy for nausea, stomach pain, and other health issues.

Antioxidants and other nutrients in ginger may help prevent or treat arthritis, inflammation, and various types of infection. Researchers have also studied its potential to reduce the risk of diabetes, cancer, and other health problems. Ginger also helps your liver and kidneys detox.

What Does Ginger Do For The Kidneys?

The kidneys flush water-soluble waste in response to water and electrolyte concentrations. Foods that support kidneys and a daily kidney cleanse as part of daily diet on a regular basis such as ginger tea is great as a kidney cleanse support. To support detoxification, drinking ginger teas, which are weak diuretics promote kidney detox without throwing electrolytes out of balance. Ginger has vitamin C, magnesium and other minerals that on regular consumption in the form of ginger tea can dissolve and prevent kidney stone formation. Ginger teas flush the kidneys and promote healthy blood pressure and also act as renal tonics to flush extra toxins and prevent bacteria build-up.

Ginger tea can have powerful effect on kidney functions. It’s been shown to increase the body’s natural antioxidants in the kidneys, lower renal inflammation, help remove toxins from the kidneys, reduce fibrosis in kidneys and help create healthier kidney tissues. Sipping ginger tea regularly can specifically help cure kidney problems.

Studies indicate that extracts of ginger, particularly the ethanol, resulted as an attractive candidate for the treatment of kidney stones induced by toxins through scavenging free radicals, improved kidney functions, inhibition of inflammatory mediators, and normalizing the kidney histopathological architecture.

What Does Ginger Do For The Liver?

Ginger cleanses the body by stimulating digestion, circulation and sweating. Its digestive actions may serve to cleanse the build-up of waste and toxins in various organs, most importantly, the liver. This action may protect against liver fibrosis which a form of degenerative scar formation. According to a study published in the June 2011 issue of the journal “Nutrition and Metabolism”, researchers tested several extracts of ginger and found that all extracts increased levels of important antioxidant enzymes used by the liver, including glutathione and superoxide dismutase. Thus, ginger has the capability to protect liver cells against damage by free radicals. Researchers concluded that ginger shows potential for use in the treatment of liver diseases.

• Ginger may help protect liver from toxic effects of drugs

• Ginger may help slow down aging-related liver damage

• It may protect from the detrimental effects of heavy metals

• Protects the liver from scarring and fat accumulation

1. GNC PRINCE OF PEACE GINGER HONEY CRYSTALS for $4.99

2. Puritan's Pride Prince Of Peace Ginger Honey Crystals 2 for $19.99

3. Yogi Tea, Organic Ginger, Caffeine Free, 16 Tea Bags for $4.31

Extrabux is an international cashback shopping site, offering up to 30% cashback from 10,000+ Stores!

iHerb, Walgreens, Gousto, Orgain, Puritan's Pride, Pharmaca, Texas Superfood, Lloyds Pharmacy, Rite Aid, Dr. Schulze's, Vitacost, Myprotein AU, Vitabiotics, etc.

Join to get $20 welcome bonus now! (How does Welcome Bonus work?)